Although there are a variety of viruses that can cause infections
in the lower respiratory tract in children and adults, influenza A
& B, respiratory syncytial virus (RSV), influenza For 1, 2 and 3
and Adenovirus are often the most common. Symptoms of respiratory
disease caused by Adenovirus includes from the common cold to
pneumonia, "croup", and bronchitis. There are 47 serotype of
adenovirus, causing different disease from conjunctivitis,
bronchitis, pneumonia, diarrhea and other symptoms. Among them, the
serotypes of 8, 14, 16,and 17 have been shown to cause
conjunctivitis, while serotypes 7, 14, 21 cause respiratory
symptoms.
The antibodies used in the current test kit has a wide range of
reactivity against many serotypes of adenovirus, including
serotypes of 1, 2, 3, 4, 5, 6, 7, 8, 11, 14, 16, 17, 19 and 37.1
Respiratory Syncytial Virus (RSV), which causes infection of the
lungs and breathing passages, is a major cause of respiratory
illness in young children.
In adults, it may only produce symptoms of a common cold, such as a
stuffy or runny nose, sore throat, mild headache, cough, fever, and
a general feeling of being ill.
But in premature babies and kids with diseases that affect the
lungs, heart, or immune system, RSV infections can lead to other
more serious illnesses. 2 RSV is highly contagious and can be
spread through droplets containing the virus when someone coughs or
sneezes. It also can live on surfaces (such as countertops or
doorknobs) and on hands and clothing, so it can be easily spread
when a person touches something contaminated.
RSV can spread rapidly through schools and childcare centers.
Babies often get it when older kids carry the virus home from
school and pass it to them. Almost all kids are infected with RSV
at least once by the time they're 2-3 years old. 3 RSV infections
often occur in epidemics that last from late fall through early
spring. Respiratory illness caused by RSV — such as bronchiolitis
or pneumonia — usually lasts about a week, but some cases may last
several weeks.
The Adenovirus and RSV Combo Rapid Test Cassette (Nasopharyngeal
Swab) qualitatively detects the presence of Adenovirus, Respiratory
Syncytial Virus antigens in Nasopharyngeal swab specimens,
providing results within 15 minutes. The test uses antibodies
specific for Adenovirus, Respiratory Syncytial Virus to selectively
detect Adenovirus, Respiratory Syncytial Virus antigens in
Nasopharyngeal swab specimens.
How to use?
Allow the test, specimen, extraction buffer to equilibrate to room
temperature (15-30°C) prior to testing.
1. Remove the test cassette from the sealed foil pouch and use it
as soon as possible. Best results will be obtained if the assay is
performed immediately after opening the foil pouch.
2. Place the Extraction Tube in the workstation. Hold the
extraction reagent bottle upside down vertically. Squeeze the
bottle and let the solution drop into the extraction tube freely
without touching the edge of the tube. Add 10 drops of solution
(Approx. 400μL) to the Extraction Tube. See illustration 1.
3. Place the swab specimen in the Extraction Tube. Rotate the swab
for approximately 10 seconds while pressing the head against the
inside of the tube to release the antigen in the swab. See
illustration 2.
4. Remove the swab while squeezing the swab head against the inside
of the Extraction Tube as you remove it to expel as much liquid as
possible from the swab. Discard the swab in accordance with your
biohazard waste disposal protocol. See illustration 3.
5. Fit the dropper tip on top of the extraction tube. Place the
test cassette on a clean and level surface. See illustration 4.
6. Add three drops of the solution (approx.120μL) to each sample
well and then start the timer. Read the result at 15 minutes. Do
not interpret the result after 20 minutes.
INTERPRETATION OF RESULTS
(Please refer to the illustration above)
POSITIVE:* Two distinct colored lines appear. One colored line
should be in the control region (C) and another colored line should
be in the test region (T).
*Note: The intensity of the color in the test line regions may vary
depending on the concentration of Adenovirus or RSV antigen present
in the specimen. Therefore, any shade of color in the test line
region should be considered positive.
NEGATIVE: One colored line appears in the control region (C). No
apparent colored line appears in the test line regions (T).
INVALID: Control line fails to appear. Insufficient specimen volume
or incorrect procedural techniques are the most likely reasons for
control line failure. Review the procedure and repeat the test with
a new test cassette. If the problem persists, discontinue using the
test kit immediately and contact your local distributor.
| Cat. No. | Product | Specimen | Pack |
| IRIC-525 | RSV&Influenza A+B Combo Rapid Test Cassette | Swab / Nasal Aspirate | 10T |
| IARC-525 | Adenovirus&RSV Combo Rapid Test Cassette | Nasopharyngeal Swab | 10T |
| IARI-535 | Adenovirus, RSV and Influenza A+B Combo Rapid Test Cassette | Nasopharyngeal Swab | 10T |
