A rapid test with CE certified for the qualitative detection of
Benzodia/zepines in human urine. For medical and other professional
in vitro diagnostic use only.
Applications:
The BZO Rapid Test (Urine) is a rapid chromatographic immunoassay
for the detection of Oxazepam (major metabolite) in urine at a
cut-off concentration of 300ng/ml. This test will detect other
related compounds, please refer to the Analytical Specificity table
in this package insert.
This assay provides only a qualitative, preliminary analytical test
result. A more specific alternate chemical method must be used in
order to obtain a confirmed analytical result.
Gas chromatography/mass spectrometry (GC/MS) is the preferred
confirmatory method. Clinical consideration and professional
judgment should be applied to any drug of abuse test result,
particularly when preliminary positive results are used.
Description:
Benzodiaz/epines are medications that are frequently prescribed for
the symptomatic treatment of anxiety and sleep disorders. They
produce their effects via specific receptors involving a
neurochemical called gamma aminobutyric acid (GABA). Because they
are safer and more effective, Benzo/diazepines have replaced
Barbitur/ates in the treatment of both anxiety and insomnia.
Benzodia/zepines are also used as sedatives before some surgical
and medical procedures, and for the treatment of seizure disorders
and alcohol withdrawal.
Risk of physical dependence increases if Benzodia/zepines are taken
regularly (e.g., daily) for more than a few months, especially at
higher than normal doses.
Stopping abruptly can bring on such symptoms as trouble sleeping,
gastrointestinal upset, feeling unwell, loss of appetite, sweating,
trembling, weakness, anxiety and changes in perception. Only trace
amounts (less than 1%) of most Benzodiaz/epines are excreted
unaltered in the urine; most of the concentration in urine is
conjugated drug. The detection period for the Benzod/iazepines in
the urine is 3-7 days.
How to use?
Allow the test, urine specimen, and/or controls to reach room
temperature (15-30°C) prior to testing.
1. Bring the pouch to room temperature before opening it. Remove
the test cassette from the sealed pouch and use it within one hour.
2. Place the test cassette on a clean and level surface. Hold the
dropper vertically and transfer 3 full drops of urine (approx.
120μL) to the specimen well (S) of the test cassette, and then
start the timer. Avoid trapping air bubbles in the specimen well
(S). See the illustration below.
3. Wait for the colored line(s) to appear. Read results at 5
minutes. Do not interpret the result after 10minutes.
DIRECTIONS FOR PANEL USE
Allow the test, urine specimen, and/or controls to reach room
temperature (15-30ºC) prior to testing.
1. Bring the pouch to room temperature before opening it. Remove
the test panel from the sealed pouch and use it within one hour.
2. Remove the cap.
3. With the arrow pointing toward the urine specimen, immerse the
test panel vertically in the urine specimen for at least 10 to 15
seconds. Immerse the strip to at least the level of the wavy lines,
but not above the arrow on the test panel.
4. Replace the cap and place the test panel on a non-absorbent flat
surface.
5. Start the timer and wait for the colored line(s) to appear.
6. The result should be read at 5 minutes. Do not interpret the
result after 10 minutes.
DIRECTIONS FOR DIPSTICK USE
Allow the test, urine specimen, and/or controls to reach room
temperature (15-30ºC) prior to testing.
1. Bring the pouch to room temperature before opening it. Remove
the test dipstick from the sealed pouch and use it within one hour.
2. With arrows pointing toward the urine specimen, immerse the test
dipstick vertically in the urine specimen for at least 10-15
seconds. Do not pass the maximum line (MAX) on the Test Dipstick
when immersing the strip. See the illustration below.
3. Place the test dipstick on a non-absorbent flat surface, start
the timer and wait for the colored line(s) to appear. Read results
at 5 minutes. Do not interpret the result after 10 minutes.
INTERPRETATION OF RESULTS
(Please refer to the illustration above)
NEGATIVE:* Two lines appear. One colored line should be in the
control line region (C), and another apparent colored line should
be in the test line region (T). A negative result indicates that
the Benzo/diazepines (BZO) concentration is below the detectable
level.
*NOTE: The shade of color in the test line region (T) may vary, but
it should be considered negative whenever there is even a faint
colored line.
POSITIVE: One colored line appears in the control line region (C).
No line appears in the test line region (T). A positive result
indicates that the Benzodiaze/pines (BZO) concentration exceeds the
detectable level.
INVALID: Control line fails to appear. Insufficient specimen volume
or incorrect procedural techniques are the most likely reasons for
control line failure. Review the procedure and repeat the test
using a new test. If the problem persists, discontinue using the
lot immediately and contact your local distributor.
Order Information
| Cat. No. | Product Description | Specimen | Format | Kit Size | Cut-Off | Status |
|
| DBZ-102 | Benzodiazep/ines (BZO) Rapid Test Cassette | Urine | Cassette | 40 T | 100 ng/mL, 200 ng/mL,
300 ng/mL* | CE/FDA |
| DBZ-114 | Benzodiaz/epines (BZO) Rapid Test Panel | Urine | Panel | 40 T | CE/FDA |
| DBZ-101 | Benzodia/zepines (BZO) Rapid Test Dipstick | Urine | Dipstick | 50 T | CE/FDA |
